cialis drug screen

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Cialis

GENERIC NAME(S): TADALAFIL

Uses

Tadalafil is used to treat male sexual function problems (impotence or erectile dysfunction -ED). In combination with sexual stimulation, tadalafil works by increasing blood flow to the penis to help a man get and keep an erection.

Tadalafil is also used to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia -BPH ). It helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate frequently or urgently (including during the middle of the night). Tadalafil is thought to work by relaxing the smooth muscle in the prostate and bladder .

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

How to use Cialis

Read the Patient Information Leaflet provided by your pharmacist before you start taking tadalafil and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth. with or without food, as directed by your doctor. Do not take tadalafil more often than once daily.

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

To treat the symptoms of BPH. take this medication as directed by your doctor, usually once a day. If you are also taking finasteride with this medication to treat symptoms of BPH, talk with your doctor about how long you should continue taking this medication.

To treat erectile dysfunction -ED, there are 2 ways that tadalafil may be prescribed. Your doctor will determine which is the best way for you to take tadalafil. Follow your doctor's directions exactly since your dosage depends on how you are taking it. The first way is to take it as needed, usually at least 30 minutes before sexual activity. Tadalafil's effect on sexual ability may last up to 36 hours.

The second way to treat ED is to take tadalafil regularly, once a day every day. If you take it this way, you may attempt sexual activity at any time between your doses.

If you are taking tadalafil to treat both ED and BPH, take it as directed by your doctor, usually once a day. You may attempt sexual activity at any time between your doses.

If you are taking tadalafil once daily for BPH, or for ED, or for both, take it regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Tell your doctor if your condition does not improve or if it worsens.

Side Effects

Headache. stomach upset, back pain. muscle pain. stuffy nose, flushing, or dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Sexual activity may put extra strain on your heart. especially if you have heart problems. If you have heart problems and experience any of these serious side effects while having sex. stop and get medical help right away: severe dizziness, fainting. chest/jaw/left arm pain, nausea .

Rarely, sudden decreased vision. including permanent blindness, in one or both eyes (NAION) may occur. If this serious problem occurs, stop taking tadalafil and get medical help right away. You have a slightly greater chance of developing NAION if you have heart disease. diabetes. high cholesterol. certain other eye problems ("crowded disk"), high blood pressure. if you are over 50, or if you smoke.

Rarely, a sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness, may occur. Stop taking tadalafil and get medical help right away if these effects occur.

In the rare event you have a painful or prolonged erection lasting 4 or more hours, stop using this drug and get medical help right away, or permanent problems could occur.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction. including: rash, itching /swelling (especially of the face/tongue /throat), severe dizziness, trouble breathing .

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking tadalafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure), stroke in the past 6 months, kidney disease, liver disease, high or low blood pressure, a severe loss of body water (dehydration), penis conditions (such as angulation, fibrosis/scarring, Peyronie's disease), history of painful/prolonged erection (priapism), conditions that may increase the risk of priapism (such as sickle cell anemia, leukemia, multiple myeloma), eye problems (such as retinitis pigmentosa, sudden decreased vision, NAION), bleeding disorders, active stomach ulcers.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This brand of the drug is not usually used in women. During pregnancy, tadalafil should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

A product that may interact with this drug is: riociguat.

Tadalafil can cause a serious drop in your blood pressure when used with nitrates, which can lead to dizziness, fainting, and rarely heart attack or stroke. Do not use tadalafil with any of the following: certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide), recreational drugs called "poppers" containing amyl or butyl nitrite.

If you are also taking an alpha blocker medication (such as doxazosin, tamsulosin) to treat an enlarged prostate/BPH or high blood pressure, your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may start treatment with a lower dose of tadalafil or adjust your alpha blocker medication to minimize your risk of low blood pressure.

Other medications can affect the removal of tadalafil from your body, which may affect how tadalafil works. Examples include azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as clarithromycin, erythromycin), HIV protease inhibitors (such as fosamprenavir, ritonavir), hepatitis C virus protease inhibitors (such as boceprevir, telaprevir), rifampin, among others.

Do not take this medication with any other product that contains tadalafil or other similar medications used to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, vardenafil).

Overdose

If overdose is suspected, contact a poison control center or emergency room right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Do not share this medication with others.

Missed Dose

If you are taking this medication on a regular schedule and you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Information last revised October 2015. Copyright(c) 2015 First Databank, Inc.

Images

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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home > drugs a-z list > cialis (tadalafil) side effects drug center > cialis (tadalafil) drug

Cialis (tadalafil) Indications

Cialis has the following indications:

  • Treatment of erectile dysfunction (ED)
  • Treatment of signs and symptoms of benign prostatic hyperplasia (BPH)
  • Treatment of patients with both erectile dysfunction, and signs and symptoms of benign prostatic hyperplasia.

Dosage and Administration of Cialis (tadalafil)

Cialis is a selective phosphodiesterase type 5 (PDE5) inhibitor available as 2.5, 5, 10, or 20 mg tablets for oral administration

Erectile Dysfunction (used as needed)

  • For most patients the recommended starting dose is 10 mg as needed prior to anticipated sexual activity.
  • The dose may be increased to 20 mg or decreased to 5 mg based on efficacy or tolerability.
  • The maximum dosing frequency is once daily for most patients. Cialis is effective for up to 36 hours.
  • Renal dysfunction:
    • Creatinine clearance 30 to 50 ml/min: The recommended starting dose is 5 mg no more than once daily, and the maximum dose is 10 mg every 48 hours.
    • Creatinine clearance less than 30 ml/min or on hemodialysis. The maximum dose is 5 mg every 72 hours.
  • Hepatic dysfunction:
    • Mild or moderate dysfunction: Use has not been extensively evaluated. Do not exceed 10 mg daily.
    • Severe dysfunction: Use is not recommended.

Erectile Dysfunction (used daily without regard to sexual activity)

  • The recommended dose for scheduled once daily use is 2.5 mg taken at approximately the same time daily without regard to timing of sexual activity.
  • The dose may be increased to 5 mg daily based on efficacy and tolerability.
  • For patients with renal dysfunction:
    • Creatinine clearance less than 30 ml/min or on hemodialysis: Cialis is not recommended for scheduled once daily use.
  • Hepatic dysfunction:
    • Mild or moderate dysfunction: Use has not been extensively evaluated. Therefore, use with caution.
    • Severe dysfunction: Use is not recommended.

Benign prostatic hyperplasia

  • The recommended dose is 5 mg taken at approximately the same time every day.
  • Renal dysfunction:
    • Creatinine clearance 30 to 50 ml/min: Start with 2.5 mg and increase to 5 mg daily as needed and tolerated.
    • Creatinine clearance less than 30 ml/min or on hemodialysis: Cialis is not recommended for scheduled once daily use.

Combined Erectile Dysfunction and Benign prostatic hyperplasia

  • The recommended dose is 5 mg at approximately the same time every day without regard to sexual activity.
  • For patients with renal dysfunction:
    • Creatinine clearance 30 to 50 ml/min: Start with 2.5 mg and increase to 5 mg daily as needed and tolerated.
    • Creatinine clearance less than 30 ml/min or on hemodialysis: Cialis is not recommended for scheduled once daily use.
  • Hepatic dysfunction:
    • Mild or moderate dysfunction: Use has not been extensively evaluated. Therefore, use with caution.
    • Severe dysfunction: Use is not recommended.

Use with CYP3A4 inhibitors (see drug interactions)

  • Maximum dose is 10 mg every 72 hours as needed or 2.5 mg daily without regard to timing of sexual activity.

Contraindications, Warnings, and Precautions

Contraindications

  • Use of nitrates (for example, nitroglycerine, isosorbide): Cialis may increase hypotensive effects of nitrates.
  • Hypersensitivity reactions to tadalafil (Cialis or Adcirca)

Warnings and Precautions

  • Angina. Patients with angina should not use Cialis because sexual activity may precipitate angina.
  • Use of scheduled daily Cialis in combination with nitrates, alpha blockers, antihypertensives, and potent CYP3A4 inhibitors.
  • Prolonged erections and priapism
  • Sudden loss of vision: NAION (non-arteritic anterior ischemic optic neuropathy)
  • Sudden hearing loss .
  • Alpha blockers and antihypertensives: Cialis potentiates the antihypertensive effects of alpha blockers and antihypertensives.
  • Renal impairment: See dosing section.
  • Hepatic impairment: See dosing section.
  • Alcohol: Cialis potentiates the vasodilatory action of alcohol. Combining Cialis with substantial consumption of alcohol may result in orthostatic hypotension .
  • CYP3A4 inhibitors (for example, ritonavir, ketoconazole, itraconazole): Limit dose. (See drug interactions.)
  • Other PDE5 inhibitors: Cialis should not be combined with other PDE5 inhibitors.
  • Bleeding: PDE5 is found on platelets. Use of Cialis in patients with bleeding disorders or active peptic ulcers should be based on careful risk-benefit assessment and caution.

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False Positives Forum

This forum is intended to help those who Do NOT Abuse Drugs. We do NOT support the illegal use of any substance. If you have experience with false positives, share your experience. What would you tell someone about drug testing and false positives? Please remember that we do not give medical or legal advice.


Positive for Restoril
Date: 1/10/2012
I had a d and c then had to take a UA. My result shows positive for restoril, had diazepam, promethazine, ondansetron, ibuprofen, fomotidine, omeprazole, fentanyl, lidocaine, ceftriaxone, doxycycline, robitussin.
Lakeeshia

AskDocWeb: Several of your meds have shown up as false positives on urine drug tests. Ibuprofen, promethazine, and omeprazole have tested false positive for THC. Robitussin has tested false positive for opiates. However if they are testing for Restoril (Temazepam), that is a benzodiazepine. Diazepam contains benzodiazepines.


Cialis, Levitra, or Viagra?
Date: 1/11/2012
Will cialis, levitra or viagra show a false positive on a drug test?
Bob

AskDocWeb: Those drugs do not show up on a urine drug screen. They are not classified as drugs of abuse so you can enjoy a good sex life without that particular concern.


Will hydroxyzine make me fail a drug test?
Date: 1/11/2012
I just started taking hydroxyzine and I wanted to know if it would make me fail a drug test and if so what would it make me fail for?
Meagan

AskDocWeb: Hydroxyzine has not been reported to show up on urine drug tests for drugs of abuse.


Will these cause a false positive?
Date: 1/11/2012
Hello again, I have a few new medications and would like to know if they give a false positive for anything the pills are tramadol, vitamin d, levothyroxin, and asprin. I would like to know if they give a false positive for anything so when I go to another pain management doctor and they give me a drug test I will know what to expect.
Cameron

AskDocWeb: None of your medications are on the list of possible causes for false positives on urine drug screens. The only vitamin on that list is Riboflavin (vitamin B2) and that showed up only when large doses were used. However, if you start taking a new medication you may want to check it against this list.


Hard documentation about OTC meds causing false positives
Date: 1/11/2012
Is there any hard documentation available publicly showing official documentation of any OTC meds causing a false positive? If so where can I find this?
Jason

AskDocWeb: When you read through the list of causes for false positives you will see a reference number for each item. Clicking on the reference number will take you to the page that lists the sources used for references. These include the companies that make the drug testing kits and drug manufacturers.


Methylhexanamine
Date: 1/11/2012
How long will Methylhexanamine stay in blood or detect in urine.
Tatito

AskDocWeb: Methylhexaneamine has a short half-life, somewhere between 4 to 12 hours so it should be out of your system within 3 days.

Athletes should note that methylhexaneamine is often listed as something else in an ingredient list. Here are the most common names (synonyms) listed by the makers of dietary supplements and energy drinks:
  • 1,3-dimethylamylamine
  • 1,3-dimethylpentylamine
  • 2-amino-4-methylhexane
  • 2-hexanamine, 4-methyl-(9CI)
  • 2-hexanamine, 4-methyl-
  • 4-methyl-2-hexanamine
  • 4-Methylhexan-2-amine
  • DMAA
  • Floradrene
  • Forthan
  • Forthane
  • Geranamine (trademarked by Proviant Technologies)
  • Geranium extract
  • Geranium oil extract
  • Geranuim oil
  • Methylhexanamine
If you are using supplements with the above ingredients, athletes should be aware that the presence of Methylhexaneamine may cause a positive drug test because was banned by WADA. If you are not an athlete but just being tested for drugs of abuse then this may still be a problem. The U.S. National Library of Medicine confirms that dimethylamylamine may test positive for amphetamines on urine drugs tests.


Can naproxen cause a false positive?
Date: 1/14/2012
I took a drug test yesterday and I tested positive for THC. I don't do drugs. The only thing I took was naproxen. Was this the cause? And it was sent to lab to determine if I really did smoke marijuana.
Jess

AskDocWeb: Yes, Naproxen (Aleve) has been known to show up as a false positive for marijuana. The lab should be able to easily eliminate this type of false positive.


Liver problems
Date: 1/16/2012
I have liver problems and keep testing positive for t h c even though I don't use it, what is this about?
Peter

AskDocWeb: There seems to be something about liver problems or the medications used to treat them that causes urine drug tests to show false positive for THC. The reason for this is unknown but it has been happening for years. Unfortunately the "War on Drugs" discourages any research into the cause of this because it is a politically incorrect or taboo subject. Fortunately the GC-MS confirmation test can make a distinction between those who have liver disease and those who use THC.


Tested positive for opiates
Date: 1/16/2012
I have been in suboxone for 1 yr. Have NEVER had a positive drug screen..u/a. I have been on azithromycin, prednisone, phenergan, and took an ibuprofen 400mg. My Dr. Said I tested positive for opiates. could there have been a false positive? I am PROUDLY 1 YEAR clean.
Jami

AskDocWeb: If your Phenergan comes with codeine in it, that "may" be a possible explanation for the result. A quick call to your pharmacist would tell you if that were the case.


False positive for benzos
Date: 1/17/2012
I recently tested a false positive for benzos. All I have taken was Ibuprofen, Asprin, sore throat spray containing Phenol, Daytime and nighttime cold and flu medicine containing Acetaminophren, Dextromethorphan HBr, Phenylephrine HCl, and Doxylamine Succinate. I have never taken a benzo and didn't know what one was before this test. Anything known about the above?
Lawrence

AskDocWeb: Some of your meds have been known to cause a false positive on urine drug screens but not for benzos. You might check the ingredients in your sore throat spray against this list for a possible explanation.


Postive for cocaine
Date: 1/18/2012
I was test postive for cocaine but I have never taking anything but prescribed drugs such as Tramadol, cyclobenzaprine, ketorolac 10 mg, oxycodon 7.5-325.
Lesia

AskDocWeb: Hi Lesia, welcome to the forum. Although those medications are not known to cause a false positive for cocaine, your test result still might be a false positive because of other reasons. If you truly believe the results were false then you may want to get a confirmation test.


Positive for cocaine
Date: 1/18/2012
Is it possible to test (false) positive for cocaine if I am prescribed neurontin suboxone and vyvanse?
Shannon

AskDocWeb: According to the data we have collected over the past six years of research, no.

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